Apigenin modulates cardiorenal disorders in cockerel chickens experimentally infected with Newcastle disease virus (KUDU 113 strain)

BULGARIAN JOURNAL OF VETERINARY MEDICINE 2026 Open access

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Authors: O. O. Esan, D. C. Ngoma, Olalekan Taiwo Jeremiah, Fanambinantsoa Malaza Rajemison, OA Oladele, T O Ajibade, V. A. Aliyu, Temidayo Olutayo Omóbòwálé, Ademola Adetokunbo Oyagbemi, A. Adeogun, T. A. Jarikire
DOI: 10.15547/bjvm.2024-0074
Cited by: 0

Abstract

Newcastle disease (ND) is a highly contagious viral disease of avian species. It spreads easily despite widespread vaccination and remains endemic in the majority of poultry-producing regions of the world. Apigenin, a flavonoid, has antioxidant, anti-inflammatory, antibacterial, antiviral, and anti-tumour properties. One-hundred-day-old cockerel chickens were assigned into six groups of 15 each - Group A (control); Group B: ND virus (106.5 per 0.1 mL) only; Groups C & D received 100 mg/kg and 200 mg/kg of apigenin orally in addition to ND (106.5 per 0.1 mL) while groups E and F were administered only apigenin 100 mg/kg and 200 mg/kg, respectively for seven days. Results showed significantly (P

Fields of Study & Subjects

Virology and Viral Diseases Medicinal plant effects and applications Animal Nutrition and Physiology

Publication details

Journal / source
BULGARIAN JOURNAL OF VETERINARY MEDICINE
Volume
29
Issue
1
Pages
99–99
Publication date
1 March 2026
Language
EN