Сomparative analysis of cardiac magnetic resonance imaging data in patients with hypertrophic cardiomyopathy and Anderson-Fabry disease

CARDIOVASCULAR THERAPY AND PREVENTION 2026 Open access

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Authors: E. V. Gagarina, Elena A. Mershina, Roman P. Myasnikov, A. Moiseev, Olga V. Kulikova, Maria M. Kudryavtseva, S. F. Ageeva, V. E. Sinitsyn
DOI: 10.15829/1728-8800-2025-4677
Cited by: 0
References: 12

Abstract

Aim. Cardiac involvement in Anderson-Fabry disease (AFD) is often characterized by left ventricular hypertrophy (LVH), which can be mistaken for hypertrophic cardiomyopathy (HCM). The aim was to analyze and compare morphological and functional cardiac changes using multiparametric magnetic resonance imaging (MRI) in patients with AFD, HCM, and healthy volunteers. Material and methods. The study included 131 patients with HCM, 42 patients with AFD, and 18 healthy volunteers. Multiparametric cardiac MRI was performed using a 3T scanner. Results. LVH was detected in 55% of patients with AFD. Signs of myocardial fibrosis were more common in HCM than in AFD+LVH (86% vs 35%, p

Fields of Study & Subjects

Cardiomyopathy and Myosin Studies Lysosomal Storage Disorders Research Cardiac Imaging and Diagnostics

Publication details

Journal / source
CARDIOVASCULAR THERAPY AND PREVENTION
Volume
24
Issue
12
Pages
4677–4677
Publication date
8 February 2026
Language
EN