Epicardial fat thickness and serum transaminase values in myocardial infarction with concomitant metabolic-associated fatty liver disease

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Authors: V. A. Tretyakova, Ж. Д. Кобалава, Д. П. Котова, S. Radenska-Lopovok, Oleg V. Ermilov, Mikhail A Tretyakov, П. К. Алферов
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References: 22

Abstract

Aim. To assess the relationship between epicardial fat thickness (EFT) and metabolic-associated fatty liver disease (MAFLD), including hepatic steatosis (HS) and steatohepatitis, in myocardial infarction (MI), as well as to analyze the changes of transaminase levels in patients with a combination of ST-elevation MI (STEMI) and MAFLD to accurately identify liver disease. Material and methods. A total of 163 patients with ST-elevation myocardial infarction (STEMI) (n=144) and non-ST-elevation myocardial infarction (NSTEMI) (n=19) with metabolic syndrome (MetS) were admitted for primary coronary angiography and percutaneous intervention (PCI). Eighty-two patients had concomitant MAFLD (55 with steatosis and 27 with steatosis). Liver elastometry, EFT measurement, cardiac troponin I levels, alanine and aspartate aminotransferase (ALT and AST) levels, and cytokeratin-18 fragment concentrations were measured. Results. MAFLD in patients with MI compared to patients without liver pathology is associated with higher EFT (p

Fields of Study & Subjects

Cardiovascular Disease and Adiposity Liver Disease Diagnosis and Treatment Acute Myocardial Infarction Research

Publication details

Journal / source
CARDIOVASCULAR THERAPY AND PREVENTION
Volume
25
Issue
2
Pages
4482–4482
Publication date
14 March 2026
Language
EN