Comparison of artificial intelligence and rheumatologists in nailfold capillaroscopic evaluation
Abstract
OBJECTIVE: The aim of this study was to evaluate the diagnostic accuracy of a pretrained Vision Transformer model on nailfold capillaroscopy images, comparing its performance to that of expert rheumatologists. METHODS: We retrospectively analyzed 104 anonymized images (23 normal, 81 pathological) from publicly available datasets. The pretrained Vision Transformer model was applied without fine-tuning. Two rheumatologists independently assessed the same image set. Accuracy and interrater agreement were calculated. RESULTS: The AI model produced 0% clinical applicability, failing to generate meaningful classifications. In contrast, the consensus of two rheumatologists achieved the highest diagnostic performance, with 94.2% accuracy and a Cohen's Kappa of 0.827. Individual rheumatologist evaluations yielded comparatively lower accuracy and agreement. CONCLUSION: We retrospectively analyzed X anonymized images (XX normal, XX pathological) from publicly available datasets. The pretrained Vision Transformer model was applied without fine-tuning. Two rheumatologists independently assessed the same image set. Accuracy and interrater agreement were calculated.
Fields of Study & Subjects
Rheumatoid Arthritis Research and Therapies
Clinical Reasoning and Diagnostic Skills
Musculoskeletal Disorders and Rehabilitation
Publication details
- Journal / source
- Revista da Associação Médica Brasileira
- Publisher
- FapUNIFESP (SciELO)
- Volume
- 72
- Issue
- 2
- Pages
- e20251389–e20251389
- Publication date
- 1 January 2026
- Language
- EN