Transperineal Laser Ablation for Treatment of Lower Urinary Tract Symptoms in Benign Prostate Enlargement: A Systematic Review and Meta-analysis

International braz j urol 2026 Open access

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Authors: Iago Zang Pires, Marília Oberto da Silva Gobbo, Alexandre Yamada Fujimura, Tanize Louize Milbradt, Renan Yuji Ura Sudo, Mable Pereira, Nilson Marquardt Filho, Gustavo Franco Carvalhal, Márcio Augusto Averbeck
DOI: 10.1590/s1677-5538.ibju.2025.0423
Cited by: 2
References: 46

Abstract

PURPOSE: This is a systematic review and meta-analysis of the outcomes of transperineal prostate laser ablation (TPLA) in men with benign prostatic enlargement. MATERIALS AND METHODS: Pubmed, Embase, Scopus, and Cochrane Library databases were searched from inception to July 2024. Random-effects model was employed to compute mean differences for continuous endpoints. Heterogeneity was evaluated by prediction interval and I-squared statistics. Results were reported following the PRISMA guidelines. RESULTS: Seventeen studies involving 777 patients with mean age of 62 to 80 years were included. Over 12-month follow-up, TPLA decreased the International Prostate Symptom Score (MD -12.62; 95% CI -14.87 to -10.37; p

Fields of Study & Subjects

Urinary Bladder and Prostate Research Sexual function and dysfunction studies Pelvic floor disorders treatments

Publication details

Journal / source
International braz j urol
Publisher
FapUNIFESP (SciELO)
Volume
52
Issue
2
Publication date
1 April 2026
Language
EN