Disparities in time-to-treatment initiation and therapeutic modalities for malignant melanoma of the skin: a cross-sectional study, Brazil, 2013-2023

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Authors: Helena Rubini Nogueira, ENZO LOFREDO AMORIM, Geovanna Dhi Genaro, Múcio Cevulla da Silva Lourenço, VICTOR HUGO SILVA DANTAS, Luiz Vinícius de Alcantara Sousa
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References: 12

Abstract

OBJECTIVE: To analyze regional disparities in time-to-treatment initiation and initial therapeutic modalities adopted for malignant melanoma of the skin in Brazil between 2013 and 2023. METHOD: This is a cross-sectional study based on secondary data extracted from the Oncology Panel. Prevalence ratios and 95% confidence intervals for time-to-treatment initiation were estimated by treatment region and initial therapeutic modality using Poisson regression with robust variance. RESULTS: A total of 23,145 records were analyzed. Surgery was the main initial therapeutic modality in all regions, with 89.0% of procedures performed within 30 days of diagnosis, especially in the Southern region (88.6%). In contrast, chemotherapy and radiotherapy were predominantly initiated after 60 days, with the highest percentages in the Northern region (56.1% and 77.4%). CONCLUSION: Significant disparities in time-to-treatment initiation were observed between the Brazilian regions, regardless of therapeutic modality, except in the Midwest region regarding radiotherapy. The findings highlighted the need for actions to promote greater equity in access to cancer treatment, in accordance with Law No. 12732/2012, aiming to improve clinical outcomes for users.

Fields of Study & Subjects

Cutaneous Melanoma Detection and Management Global Cancer Incidence and Screening Advances in Oncology and Radiotherapy

Publication details

Journal / source
Epidemiologia e Serviços de Saúde
Volume
35
Pages
e20250025–e20250025
Publication date
1 January 2026
Language
EN