Graph-Theoretic Consistency for Robust and Topology-Aware Semi-Supervised Histopathology Segmentation (Student Abstract)

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Authors: Ha-Hieu Pham, Le Huu Nhat Minh, Hong-Han Huynh, Nguyen Quoc Khanh Le, Huy‐Hieu Pham
Cited by: 1

Abstract

Semi-supervised semantic segmentation (SSSS) is vital in computational pathology, where dense annotations are costly and limited. Existing methods often rely on pixel-level consistency, which propagates noisy pseudo-labels and produces fragmented or topologically invalid masks. We propose Topology Graph Consistency (TGC), a framework that integrates graph-theoretic constraints by aligning Laplacian spectra, component counts, and adjacency statistics between prediction graphs and references. This enforces global topology and improves segmentation accuracy. Experiments on GlaS and CRAG demonstrate that TGC achieves state-of-the-art performance under 5–10% supervision and significantly narrows the gap to full supervision.

Fields of Study & Subjects

AI in cancer detection Digital Imaging for Blood Diseases Gene expression and cancer classification

Publication details

Journal / source
Proceedings of the AAAI Conference on Artificial Intelligence
Publisher
Association for the Advancement of Artificial Intelligence (AAAI)
Volume
40
Issue
48
Pages
41354–41356
Publication date
14 March 2026
Language
EN