Interpretable Fine-Gray Deep Survival Model for Competing Risks: Predicting Post-Discharge Foot Complications for Diabetic Patients in Ontario

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Authors: Dhanesh Ramachandram, Anne Loefler, Surain B. Roberts, Maia Norman, Charles de Mestral, Conrad Pow, Fahad Razak, Amol Verma
Cited by: 0

Abstract

Model interpretability is crucial for establishing AI safety and clinician trust in medical applications for example, in survival modelling with competing risks. Recent deep learning models have attained very good predictive performance but their limited transparency, being black-box models, hinders their integration into clinical practice. To address this gap, we propose an intrinsically interpretable survival model called CRISPNAM-FG. Leveraging the structure of Neural Additive Models (NAMs) with separate projection vectors for each risk, our approach predicts the Cumulative Incidence Function using the Fine-Gray formulation, achieving high predictive power with intrinsically transparent and auditable predictions. We validated the model on several benchmark datasets and applied our model to predict future foot complications in diabetic patients across 29 Ontario hospitals (2016-2023). Our method achieves competitive performance compared to other deep survival models while providing transparency through shape functions and feature importance plots.

Fields of Study & Subjects

Diabetic Foot Ulcer Assessment and Management Medical Imaging and Analysis Total Knee Arthroplasty Outcomes

Publication details

Journal / source
Proceedings of IASEAI Conference
Volume
2
Issue
1
Pages
572–581
Publication date
15 July 2026
Language
EN