pnr cooperate with fred to regulate SOP cell fate both positively and negatively in the medial notum of Drosophila.

PubMed 2026

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Authors: Kai-Yue Song, Yi-Fei Zhang, Yao Zhang, Shu-Ting Long, Jianjun Peng, Yuandong Sun, Xiaojuan Cui, Ben-Shan Pan, Yu-Xin Chai, Xiong Wang, Jiahui Chen
DOI: 10.16288/j.yczz.25-080
Cited by: 0

Abstract

are essential for endogenous SOP formation in the medial notum, while (2) they synergistically suppress SOP initiation outside proneural clusters. These findings challenge the canonical assertion in the "Prepattern Hypothesis" that SOP formation strictly relies on proneural cluster formation, thereby providing a critical extension to the hypothesis.

Fields of Study & Subjects

Developmental Biology and Gene Regulation Neurogenesis and neuroplasticity mechanisms Neurobiology and Insect Physiology Research

Publication details

Journal / source
PubMed
Volume
48
Issue
1
Pages
87–101
Publication date
20 January 2026
Language
EN