Mechanism of tcirg1b deficiency in disrupting central nervous system homeostasis of zebrafish.

PubMed 2026

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Authors: Yu-Jie Li, Fei-Fei Li, Wen-Qing Zhang, Qi Chen
DOI: 10.16288/j.yczz.25-234
Cited by: 0

Abstract

deficiency disrupts microglial function, thereby indirectly leading to an imbalance in CNS homeostasis. Our findings reveal a key role for the V-ATPase a3 subunit in regulating neural homeostasis and offer a new theoretical framework for studying the mechanisms of neurological diseases.

Fields of Study & Subjects

Neuroinflammation and Neurodegeneration Mechanisms Zebrafish Biomedical Research Applications ATP Synthase and ATPases Research

Publication details

Journal / source
PubMed
Volume
48
Issue
2
Pages
201–212
Publication date
20 February 2026
Language
EN