A novel A-to-G mutation in circBDP1 alters adipocyte proliferation and differentiation and affects bovine carcass traits

Journal of Zhejiang University SCIENCE B 2026 Open access

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Authors: Enhui Jiang, Chiyuan Zhang, Zhuoyuan He, Yuli Zhang, Yuta Yang, Chuanying Pan, Fugui Jiang, Enliang Song, Sihuan Zhang, Xianyong Lan
DOI: 10.1631/jzus.b2500084
Cited by: 7
References: 22

Abstract

Fat deposition in cattle, influenced by factors such as genetics, age, sex, and nutrition, plays a crucial role in determining growth rates, beef yield, and meat quality. Among these, genetics is the predominant factor (Kim et al., 2020; Xing et al., 2025). Research indicates a high heritability for visceral (36%) and subcutaneous (57%) fat (Fox et al., 2012). Gene mutations that affect adipocyte function are significant contributors to variations in fat deposition and meat quality (Mannen, 2011; Mwangi et al., 2019; Sun et al., 2023; Dementieva et al., 2024). Therefore, investigating genetic variations in fat-related genes is essential for enhancing cattle performance.

Fields of Study & Subjects

Adipokines Inflammation and Metabolic Diseases Genetic and phenotypic traits in livestock Kruppel-like factors research

Publication details

Journal / source
Journal of Zhejiang University SCIENCE B
Publisher
Zhejiang University Press
Volume
27
Issue
8
Pages
918–922
Publication date
24 June 2026
Language
EN