Evaluation of the relationship between the severity of interstitial fibrosis in diagnostic renal biopsies and disease progression in primary glomerular diseases

Néphrologie & Thérapeutique 2026

View at publisher
Authors: Kadir Intas, Fatma Ayerden Ebinç, Gülay Ulusal Okyay
DOI: 10.1684/ndt.2026.171
Cited by: 0

Abstract

This single-center retrospective cohort study divided 176 adults with biopsy-proven primary glomerulonephritis (GN) between 2014 and 2021 into 4 groups based on cortical interstitial fibrosis (IF) percentage. The primary outcome was disease progression, defined as a ≥40% decline in estimated glomerular filtration rate (eGFR) and/or the need for dialysis. The secondary outcome was complete remission, defined as proteinuria

Fields of Study & Subjects

Renal Diseases and Glomerulopathies Chronic Kidney Disease and Diabetes Vasculitis and related conditions

Publication details

Journal / source
Néphrologie & Thérapeutique
Volume
22
Issue
1
Pages
36–45
Publication date
1 February 2026
Language
EN