Migraine: issues of pathogenesis and drug therapy
Abstract
The review discusses the relationship between the mechanisms of migraine pathogenesis, namely, cortical spreading depression, changes in cerebral circulation during a migraine attack and with cortical spreading depression, and the role of serotonin and the calcitonin gene-related peptide in regulating cerebral vessels and their involvement in the emergence of a migraine attack. Drugs used for the treatment and prevention of migraine, as well as new compounds being developed for the treatment and prevention of migraine attacks, are described.
Fields of Study & Subjects
Migraine and Headache Studies
Intracranial Aneurysms: Treatment and Complications
Pain Mechanisms and Treatments
Publication details
- Journal / source
- S S Korsakov Journal of Neurology and Psychiatry
- Volume
- 126
- Issue
- 1
- Pages
- 45–45
- Publication date
- 9 February 2026
- Language
- EN