Classification of non-small cell lung cancer according to the WHO 2021: from morphology to personalized therapy
Abstract
This study analyzes the modern (2021) WHO classification of lung tumors and reviews publications in Russian and English from databases including PubMed, Google Scholar, ClinicalTrials.gov, eLibrary, and CyberLeninka. The aim of this review is to identify key changes in the 2021 WHO classification compared to the 2015 edition and assess their significance for the diagnosis and personalized treatment of non-small cell lung cancer. Special attention is given to the handling of small biopsy specimens, which requires an integrated approach involving morphological examination, immunohistochemistry, and molecular genetic testing.
Fields of Study & Subjects
Lung Cancer Diagnosis and Treatment
Lung Cancer Treatments and Mutations
Lung Cancer Research Studies
Publication details
- Journal / source
- Russian Journal of Archive of Pathology
- Volume
- 88
- Issue
- 1
- Pages
- 60–60
- Publication date
- 27 January 2026
- Language
- EN