Crohn`s disease, vedolizumab and autoinmmune hemolytic anemia: coincidence or causality?

Revista Española de Enfermedades Digestivas 2026

View at publisher
Authors: Rubén Alvarado Jara, Jose Lázaro Pérez Calle, Laura Igualada Escribano, Juan Ángel Ferrer, Marta Quiñones Calvo, Rosalía González Ruiz, Pilar López Serrano
DOI: 10.17235/reed.2026.11879/2026
Cited by: 0
References: 5

Abstract

Autoimmune hemolytic anemia (AIHA) is an autoimmune destruction of red blood cells, usually mediated by immunoglobulin G (IgG) and/or immunoglobulin M (IgM). We present the case of a 75-year-old woman diagnosed with Crohn's disease (CD) who developed AIHA while receiving treatment with vedolizumab. We think that this report is important to add evidence of this possible association and most of all, underscores the importance of maintaining a high index of suspicion in patients with severe anemia and IBD undergoing treatment with novel therapies.

Fields of Study & Subjects

Inflammatory Bowel Disease Blood groups and transfusion Vasculitis and related conditions

Publication details

Journal / source
Revista Española de Enfermedades Digestivas
Volume
118
Issue
10
Pages
605–606
Publication date
1 January 2026
Language
EN