Comparative evaluation of HbA1c in point-of-care testing (POCT) devices: enzymatic and immunoassay methods compared to ion-exchange high-performance liquid chromatography (IE-HPLC)
Abstract
AIM: To evaluate 3 point-of-care testing (POCT) devices in testing HbA1c: the Simplex TASTM101 (Tascom Co. Ltd., South Korea), which utilizes an enzymatic method, and two immunoassay-based devices, the Zybio Q8 Pro and Zybio EXR 110 (Zybio Inc., China). METHODS: A total of 40 whole blood samples with EDTA anticoagulant were collected patients undergoing HbA1c testing at the outpatient department. The samples were analyzed using 3 POCT devices and one reference method. RESULTS: Passing-Bablok regression revealed no significant fixed or proportional bias. Strong correlations with the gold standard were observed for Simplex TASTM101 (r=0.944), Zybio Q8 Pro (r=0.910), and Zybio EXR 110 (r=0.839), all with p
Fields of Study & Subjects
Clinical Laboratory Practices and Quality Control
Diabetes Management and Research
Advanced Glycation End Products research
Publication details
- Journal / source
- Medicinski Glasnik
- Volume
- 23
- Issue
- 1
- Pages
- 18–22
- Publication date
- 27 February 2026
- Language
- EN