Prognostic Value of Computed Tomography-Derived Membranous Septum Length in Post-TAVI Conduction Abnormalities: An Updated Systematic Review and Meta- Analysis v1

This protocol describes an updated systematic review and meta-analysis designed to evaluate the prognostic value of pre-procedural computed tomography (CT)–derived membranous septum length (MSL) for predicting new-onset conduction abnormalities following transcatheter aortic valve implantation or replacement (TAVI/TAVR). The review will synthesize evidence from observational studies using standardized methods for study selection, data extraction, and risk-of-bias assessment. The expected outcome of this study is to clarify whether MSL measured on pre-procedural CT can reliably identify patients at increased risk of post-procedural conduction disturbances. The findings are anticipated to inform pre-procedural risk stratification, procedural planning, and patient counseling in TAVI/TAVR.