Nuclear Isolation for Single-Nucleus Multiomic Profiling of Mouse Brain and Spinal Cord v1

2026 Preprint Open access

Read full text
Authors: Liliana Cano Gomez, Satoshi Ishishita, Allan‐Hermann Pool
DOI: 10.17504/protocols.io.e6nvwnmo9vmk/v1
Cited by: 0

Abstract

Protocol generating suspensions of mouse neuronal nuclei (NeuN+) from central nervous system tissue for single-nucleus multiomic profiling.

Fields of Study & Subjects

Single-cell and spatial transcriptomics Genomics and Chromatin Dynamics Metabolomics and Mass Spectrometry Studies

Publication details

Publication date
5 February 2026
Document type
Preprint