In Vivo Opto-Tagging and Extracellular Recording (Acute and Chronic) v1
Abstract
This protocol describes in vivo extracellular recordings with opto-tagging of VTA units in acute and chronic configurations. Extracellular data are acquired using the Open Ephys acquisition system with Intan headstages at 30 kHz sampling. Opto-tagging is performed using brief light pulses to identify ChR2- and Chrimson-expressing units, followed by additional stimulation protocols as required.
Fields of Study & Subjects
Neuroscience and Neural Engineering
Photoreceptor and optogenetics research
Neurotransmitter Receptor Influence on Behavior
Publication details
- Publication date
- 16 February 2026
- Language
- EN
- Document type
- Preprint