Large-Scale Growth-Based Mammalian Cell Assay v1
Abstract
Where a competitive growth-based assay in HeLa cells (using the Bxb1 landing-pad system) has been validated, this protocol describes how to perform a high-throughput screen and subsequently generate a variant effect map using TileSeq.
Fields of Study & Subjects
CRISPR and Genetic Engineering
Virus-based gene therapy research
Bacterial Genetics and Biotechnology
Publication details
- Publication date
- 26 January 2026
- Document type
- Preprint