Systematic Review Protocol: The Descriptive, Functional, and Clinical Anatomy of the Interthalamic Adhesion

This systematic review provides a comprehensive synthesis of the interthalamic adhesion (ITA) in humans, integrating morphological, functional, clinical and surgical findings. Included studies encompass postmortem dissections, neuroimaging investigations, and anatomical reports published up to January 2026. Data were manually extracted by a single reviewer, including study characteristics, population demographics, morphology, functional associations, clinical correlations, and surgical relevance of the ITA. The review employs a descriptive narrative synthesis due to heterogeneity in study design, outcomes, and measurement methods. The review protocol adheres to the PRISMA 2020 guidelines and was retrospectively registered for transparency and reproducibility.