LEVANTAMENTO DE SINAIS E SINTOMAIS PARA DETECÇÃO E MONITORAMENTO DA RABDOMIÓLISE EM PACIENTES

This study aims to investigate the risks associated with rhabdomyolysis in critically ill patients admitted to intensive care units (ICUs), highlighting evidence-based strategies for early detection and reduction of mortality. Rhabdomyolysis, a condition characterized by the destruction of skeletal muscle fibers and the release of their intracellular components, has been associated with serious complications such as acute kidney injury (AKI) and multiple organ failure. In the context of ICU patients, early detection and continuous monitoring are essential to mitigate adverse outcomes and improve survival rates. Justification and Relevance Rhabdomyolysis can occur for several reasons, including trauma, severe infections, extreme physical activity, and medication use. The release of myoglobin, one of the main substances present in muscle cells, is one of the critical factors contributing to acute kidney injury and is an indicator of severity. Investigating risk factors and early management strategies can make important contributions to reducing mortality associated with the condition. This study aims to investigate the risks associated with rhabdomyolysis in critically ill patients admitted to intensive care units (ICUs), highlighting evidence-based strategies for early detection and reduction of mortality. Rhabdomyolysis, a condition characterized by the destruction of skeletal muscle fibers and the release of their intracellular components, has been associated with serious complications such as acute kidney injury (AKI) and The use of biomarkers such as creatine kinase (CK) and myoglobin, in combination with advanced technologies such as machine learning algorithms, has proven effective in the early detection of rhabdomyolysis, allowing for timely and appropriate interventions. This study aims to consolidate best practices for monitoring and managing this condition in critically ill patients, focusing on aggressive rehydration and electrolyte control protocols, which are fundamental practices in the treatment of rhabdomyolysis and ARF. Methodology This study was conducted through an integrative literature review, based on searches in major scientific databases, such as PubMed, Embase, SciELO, and LILACS. The descriptors used included “rhabdomyolysis,” “Intensive Care Units,” “trauma,” “evidence-based medicine,” and “advanced nursing practice,” among others. The searches were refined using Boolean operators such as “AND” and “OR” to ensure comprehensive coverage of publications relevant to the topic. The review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, ensuring transparency and methodological rigor. A total of 10 studies were included in the review, all selected because they met the inclusion criteria and provided relevant data on risk factors, clinical impact, and management strategies for ARF-associated rhabdomyolysis in ICU patients.