Autologous Fat Grafting for Vulvar Pain and Dyspareunia: A Scoping Review of Clinical Evidence

Project Description This project contains the registered protocol for a scoping review entitled: “Autologous Fat Grafting for Vulvar Pain and Dyspareunia: A Scoping Review of Clinical Evidence.” Chronic vulvar pain conditions, including vulvodynia and vestibulodynia, significantly impact sexual function and quality of life. Emerging regenerative approaches such as autologous fat grafting and adipose-derived cell–based therapies have been increasingly applied in inflammatory, fibrotic, and atrophic vulvar phenotypes. However, the available clinical evidence remains heterogeneous and has not been systematically mapped. This scoping review aims to: Identify and characterize existing clinical studies on lipofilling in vulvar pain disorders. Describe reported outcomes (pain, dyspareunia, sexual function, safety). Stratify findings by clinical phenotype. Identify methodological gaps and research priorities. The review follows Joanna Briggs Institute (JBI) methodology and PRISMA-ScR reporting guidelines. All search strategies, screening logs, data extraction forms, and final PRISMA diagram will be archived within this OSF project.