Diffusion Tensor Imaging and Advanced Diffusion Imaging in Post-Stroke Aphasia Recovery

This project is a comprehensive scoping review examining the role of diffusion MRI techniques in understanding, predicting, and guiding recovery in post-stroke aphasia (PSA). The primary purpose is to synthesize and map the existing literature on how white-matter integrity, assessed using diffusion imaging, relates to language impairment and recovery following stroke. In particular, the review aims to evaluate the clinical utility of conventional diffusion tensor imaging (DTI) alongside advanced diffusion models—such as diffusion kurtosis imaging, high-angular resolution diffusion imaging, constrained spherical deconvolution, fixel-based analysis, and connectome-based approaches—in diagnostic, prognostic, and therapeutic contexts.