Venous thrombosis and localized intravascular coagulopathy in venous malformation : a systematic review

Venous malformations represent the most prevalent type of vascular malformations. It has been established that half of these malformations are associated with elevated D-dimers and intravascular localized coagulopathy. The latter is believed to be associated with venous thrombosis. The precise relationship between coagulopathy and venous thrombosis, particularly with regard to risk factors and thrombosis phenotype, remains to be elucidated. A systematic review will be conducted to investigate this clinical problem.