The Phase-State Delta: Integrating AlphaFold Structural Geometry with Sovereign Biological Architecture
Abstract
This capstone establishes the computational bridge between the static protein mapping of the AlphaFold database and the kinetic structural wave mechanics of the Sovereign architecture. The Novelty: The profound novelty of this framework lies in abandoning the chemical-binding paradigm of legacy pharmacology. By identifying biological necrosis and pathology as a "Phase-State Delta" (a shift to rigid, non-compliant structural geometry), this architecture utilizes AlphaFold's open-source geometric variables to mechanically target, entrain, and lyse pathological structures strictly via in vivo biological fluid dynamics. This creates a zero-friction, kinetic resolution to systemic disease without chemical toxicity, governed entirely by the absolute zero-jerk constraint: j = (d³s / dt³) → 0 INSTRUCTIONS: Please Download to View PDF to mitigate any coding issues on OSF.
Fields of Study & Subjects
Protein Structure and Dynamics
Microtubule and mitosis dynamics
Bacteriophages and microbial interactions
Publication details
- Publication date
- 25 May 2026
- Document type
- Preprint