Pituitary Radiosurgery for Opioid‑Refractory Cancer Pain: An Umbrella Review

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Authors: Eunice Dalet Farfán, Sergio Moreno Jiménez, Monica Serramo-Murillo, Guillermo Axayacalt Gutiérrez-Aceves, Talía Wegman-Ostrosky, Bernardo Cacho Díaz, Dharely Raquel Cid-Sánchez, Andrea García Bitar, Alejandro Rdoriguez Camacho, Enrique Caballé‐Perez
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Abstract

This OSF project contains the protocol materials and reproducibility files for an umbrella review titled “Pituitary Radiosurgery for Opioid‑Refractory Cancer Pain: An Umbrella Review of Systematic Reviews and Meta‑Analyses.” The project includes a protocol snapshot (methods), full electronic search strategies (Supplementary File S1), PRISMA documentation, SRMA methodological appraisal using AMSTAR‑2 (including a domain heatmap), overlap assessment using a citation matrix and corrected covered area (CCA), and a GRADE‑consistent certainty assessment summarized in tables/figures. Searches covered database inception through 14 January 2026 (PubMed/MEDLINE, Scopus, Web of Science Core Collection, Cochrane Library, Epistemonikos, and LILACS). This project is being publicly archived to time‑stamp and preserve the review methods and supporting materials; copyrighted full‑text PDFs are not redistributed.

Fields of Study & Subjects

Pain Management and Opioid Use Pain Management and Treatment Pituitary Gland Disorders and Treatments

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
1 January 2026
Document type
Preprint