Plesiomonas shigelloides Bacteremia: Epidemiology, Clinical Characteristics, Outcomes, and Antimicrobial Stewardship Implications

This project is a scoping review of Plesiomonas shigelloides bacteremia, aiming to systematically synthesize the current literature on its epidemiology, clinical characteristics, outcomes, and antimicrobial stewardship implications. The review focuses on human cases reported in case reports, case series, and cohort studies, with no restriction on publication year. The main objectives are to: 1. Characterize the epidemiology and host risk factors associated with P. shigelloides bloodstream infection. 2. Describe clinical manifestations and disease severity. 3. Summarize antimicrobial susceptibility patterns reported in the literature. 4. Describe patient outcomes (mortality). All retrieved records were deduplicated in EndNote, screened independently by two authors, and data were extracted using a standardized Excel spreadsheet. Discrepancies were resolved by consensus to minimize bias. A narrative synthesis was conducted to summarize the findings, with descriptive statistics reported where appropriate. This protocol is being registered retrospectively, after completion of data extraction, to enhance transparency and reproducibility. All methods described reflect the approach actually applied in the review. Expected outcomes include a comprehensive overview of the clinical and epidemiological profile of P. shigelloides bacteremia, identification of patterns in antimicrobial resistance, and insights into strategies for antimicrobial stewardship.