MOFNet v3.0 - Advanced 8-Parameter Multi-Organ Failure Prediction System

OSF Preprints (OSF Preprints) 2026 Preprint Open access

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Authors: Samir Baladi
DOI: 10.17605/osf.io/t8qkr
Cited by: 0

Abstract

MOFNet v3.0 is an advanced clinical decision support system that predicts multi-organ failure in ICU patients using 8 physiological parameters. The system employs network medicine principles and transfer entropy to analyze cardiovascular, respiratory, neurological, renal, and metabolic functions. Enhanced Physiological Resilience Index (ePRI) provides 15.3-hour early warning with 93.7% AUC accuracy across 2,156 patients in 8 medical centers.

Fields of Study & Subjects

Sepsis Diagnosis and Treatment Heart Failure Treatment and Management Machine Learning in Healthcare

Publication details

Journal / source
OSF Preprints (OSF Preprints)
Publication date
1 January 2026
Language
EN
Document type
Preprint