HLA Association with ALL
Abstract
This retrospective case–control study analyzed 137 ALL patients and 350 ethnically-matched controls using six‑digit NGS typing of HLA‑A, ‑B, ‑C, ‑DRB1, ‑DQA1, ‑DQB1, and ‑DPB1 loci. NGS-based high-resolution typing identified novel, population-specific HLA associations with ALL in ethnic Kazakhs, with class II effects predominating and additional class I signals at HLA-B and HLA-C.
Fields of Study & Subjects
Acute Lymphoblastic Leukemia research
Genetic Associations and Epidemiology
Immunodeficiency and Autoimmune Disorders
Publication details
- Journal / source
- Mendeley Data
- Publication date
- 26 February 2026
- Language
- EN
- Document type
- Dataset