Original data on 《RatA regulates growth, biofilm formation, motility, and virulence in avian pathogenic Escherichia coli》

Avian pathogenic Escherichia coli (APEC) causes colibacillosis, incurring significant economic losses. Toxin-antitoxin (TA) systems regulate bacterial virulence, biofilm formation, and antibiotic resistance. The study focuses on RatA, a toxin characterized as a ribosomal large subunit from our Tn5 transposon mutant library biofilm screen. In the clinical isolate APEC81, ratA is co-transcribed with its putative antitoxin gene, ratB, in the ratAB operon. The study aims to characterize the function of ratA in APEC and determine if ratB affects its regulation. The methods for data collection during the research process can be found in the detailed description provided in the article.