Engineered Heart Tissues formed with Cardiac Progenitors and Differentiated Cardiomyocytes Exhibit Similar Physiologic Properties at Differentiation-Matched Timepoints [dataset]

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Authors: Aryan, Lavanya, Esteves, Jennifer A. E., Tabor, James, Jordan, Samuel D., Carey, Angela, Jiang, Huanzhu, Huebsch, Nathaniel, Rentschler, Stacey L.
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Abstract

This dataset contains supporting data for the publication "Engineered Heart Tissues formed with Cardiac Progenitors and Differentiated Cardiomyocytes Exhibit Similar Physiologic Properties at Differentiation-Matched Timepoints". This study demonstrated that induced pluripotent stem cell-derived cardiovascular progenitors (iPSC-CVP) can be used to form functional engineered heart tissues with similar electrophysiological properties to tissues formed from fully differentiated induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM), while also being more amenable to enzymatic dissociation and mechanical manipulation.

Publication details

Journal / source
Mendeley Data
Publication date
16 March 2026
Document type
Dataset