Antitumor Effects of the Novel Docetaxel Derivative JJH201601 in Glioma: Targeting Ribosome Biogenesis and Enhancing Temozolomide Sensitivity

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Authors: Zhigang Zhao, Ruiqi Jiang, Mingnan Cao, Dan Liu, Meiyu Shang, Shuxian Yang, Luofei Zhang, Nan Ji
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Abstract

RNA sequencing This study's total RNA extraction, library building, and sequencing were outsourced to Novogene Co., Ltd. In brief, RNA was extracted with Trizol reagent and quality was evaluated. Details are available in the supplemental materials. The index-coded samples were clustered using a cBot Cluster Generation System with TruSeq PE Cluster Kit v3-cBot-HS (Illumina) following the manufacturer's instructions. Following cluster creation, the library preparations were sequenced using an Illumina Novaseq technology to obtain 150 bp paired end reads.

Fields of Study & Subjects

Glioma Diagnosis and Treatment Cancer Treatment and Pharmacology Heterocyclic Compound Synthesis and Bioactivity

Publication details

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Publication date
24 February 2026
Language
EN
Document type
Dataset