Gold nanoparticles coated with cetuximab induce apoptosis in cancer cells even under non-physiologic conditions raw data

This document presents the raw data regarding the effects of acidic and alkaline solutions, temperature and buffers on the colloidal stability of uncovered gold nanoparticles and functionalized gold nanoparticles with PEG and cetuximab, a monoclonal antibody. Our hypotesis is centered whether covered gold nanoparticles surface protects these nanoparticles of aggregation. Moreover, the nanoplatform cetuximab-gold nanoparticles mantains its EGFR targeting affinity independentlly of pH and temperature evaluated mimicking tumor microenvironment fashion. To validade this hypothesis a setup of charactterization was performed, mainly spectroscopy. The raw data available here can shed light on the challenges of collecting a such data, as well as can inspire other researdchs to choose more adequate characterization setups to help them to get answears from hypothesis related to colloidal stability of bare and functionalized gold nanoparticles.