Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Mendeley Data 2026 Dataset Open access

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Authors: Jianyun Jiang
DOI: 10.17632/j2rjmxyyfw
Cited by: 0

Abstract

Enrichment of DNMT1 at the MEN1 promoter was calculated relative to input DNA and normalized against IgG isotype control immunoprecipitations. To examine region-specific recruitment, we performed ChIP-qPCR targeting two distinct regions within the MEN1 promoter (P1 and P2), together with a negative control region (P3). The primer sequences used for qPCR are listed below: P1 region: Forward 5′-GCCAATCCCTGAGTATCTC-3′; Reverse 5′-CGCTGAGCCTGGAAATAG-3′ P2 region: Forward 5′-ATCACAGCTACTCGGGAG-3′; Reverse 5′-ACACGGTCTTTCTCTTTCG-3′

Fields of Study & Subjects

Neuroendocrine Tumor Research Advances Sirtuins and Resveratrol in Medicine Pancreatic and Hepatic Oncology Research

Publication details

Journal / source
Mendeley Data
Publication date
6 March 2026
Language
EN
Document type
Dataset