EGFR Promotes Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway
Abstract
Figure 1. Interaction between the PEDV spike protein and EGFR. Figure 2. EGFR is involved in the early stage of PEDV infection. Figure 3. EGFR does not affect PEDV attachment to the cell surface. Figure 4. EGFR is involved in PEDV internalization. Figure 5. EGFR participates in the endolysosomal trafficking of PEDV. Figure 6. EGFR knockout reduces co‑localization of PEDV with late endosomes.
Fields of Study & Subjects
Animal Virus Infections Studies
Cellular transport and secretion
Viral gastroenteritis research and epidemiology
Publication details
- Journal / source
- Mendeley Data
- Publication date
- 9 February 2026
- Language
- EN
- Document type
- Dataset