Online Mindfulness-Based Cognitive Therapy as an Adjuvant-Treatment for Patients with Psoriasis: A Randomized Controlled Trial

To evaluate online Mindfulness-Based Cognitive Therapy (MBCT) as an adjuvant treatment for psoriasis, focusing on severity of lesion, anxiety, depression, quality of life, and itching. This randomized trial enrolled 109 psoriasis patients assigned to either treatment as usual (TAU) or TAU plus MBCT, which included eight weekly online sessions. Primary outcomes, included Psoriasis Area and Severity Index (PASI), Self-Rating Anxiety/Depression Scale (SAS/SDS), and Dermatology Life Quality Index (DLQI). Itching was a secondary outcome measured by Visual Analogue Scale (VAS). Assessments were conducted at baseline, 4, 8, and 12 weeks. Treatment effects were analyzed with mixed linear models. 91 patients completed the full follow-up: 46 in the MBCT+TAU group and 45 in the TAU group. Significant group × time interactions favoring MBCT+TAU were observed for PASI, SDS, DLQI and VAS. No significant between-group difference was found for anxiety.