Dataset of Anticancer Drug Responses in Mouse Xenograft Models

This dataset compiles quantitative preclinical response data for anticancer drugs evaluated in mouse xenograft models. It comprises 1,602 experimental records curated from 143 peer-reviewed source publications, covering four major cancer types: breast, colon, colorectal, and lung cancer. Each record provides standardized information on treatment characteristics, including drug type, dose, administration route, and dosing regimen, as well as model-related variables such as mouse strain, tumor model, xenograft type (PDX/CDX), genetic alterations, and implantation site. The dataset also includes efficacy and toxicity endpoints, including tumor volume and tumor weight relative to control groups, maximum body-weight loss, initial tumor volume, and corresponding endpoint-day information where available.