Sentinel lymph node biopsy during radical prostatectomy in patients with prostate cancer: literature review

Prostate cancer is one of the most frequently diagnosed oncological diseases worldwide and in the Russian Federation. Modern extended pelvic lymph node dissection is the most reliable method for detecting metastases in regional lymph nodes in patients with prostate cancer. However, this method is associated with certain risks both during the operation and in the postoperative period, which encourages researchers to develop alternative diagnostic approaches. One such alternative is sentinel lymph node biopsy, which demonstrates high potential in diagnostics. At the same time, a number of factors must be considered: limited number of randomized clinical trials, diversity of protocols used, variability of radioisotope and tracer combinations, as well as the need to consider both instrumental and clinical data. For the widespread implementation of this approach in clinical practice, further scientific research is required, including studies conducted in Russia.