Myasthenia gravis in the Republic of Bashkortostan: analysis of clinical and functional features

Background. Myasthenia gravis (MG) is a chronic autoimmune disease that significantly affects patients’ quality of life. Studying the regional characteristics of MG is important for optimizing medical care. Aim. To study the socio-demographic and clinical-functional characteristics of patients with MG in the Republic of Bashkortostan. Materials and methods. A cross-sectional study was conducted based on data from the Republican Medical Information and Analytical System as of 01.01.2024. Data from 249 patients diagnosed with MG (G70.0) were analyzed. Results. Data from 249 patients with MG were analyzed. Women (70.3 %) and individuals over 50 years of age (69 %) predominated among them. The mean age of disease onset was 43.1 years. The generalized form of MG was diagnosed in 86.7 % of patients and was significantly more common in women. Approximately half of the patients had a disability. During the year, 63.4 % of patients visited a neurologist on an outpatient basis, and 52.2 % received inpatient treatment. All patients received pyridostigmine bromide, in combination with glucocorticoids – 66.6 %, and with cytostatics – 2.8 %. Thymectomy was performed in 12.4 % of patients. High comorbidity was noted: on average, there were 3 comorbid conditions per patient. Conclusion. The study results demonstrate the high medical and social significance of MG in the Republic of Bashkortostan. Enhancement of outpatient medical care for patients with myasthenia gravis in the Republic of Bashkortostan and implementation of more personalized treatment approaches are required.