A relation between stereoelectroencephalography parameters and focal drug-resistant epilepsy surgery outcomes

Background . Stereoelectroencephalography (stereo-EEG) parameters may be predictors of surgical treatment outcomes in patients with focal drug-resistant epilepsy (fDRE). Objective : To assess a relationship between stereo-EEG parameters and surgical treatment for fDRE outcome. Material and methods . The stereo-EEG parameters were retrospectively evaluated in fDRE patients examined in 2016–2020. We reviewed the following parameters: patient’s gender, age at stereo-EEG examination, lesion presence and lateralization on magnetic resonance images, seizure onset zone localization and size, seizure pattern type, latency and propagation. These parameter-related effect on surgical treatment outcomes in fDRE patients were analyzed. Results . The outcome of surgical treatment was found to depend on the size of epileptic seizure onset zone (p=0.002). No other analyzed parameters appeared to have an impact on epilepsy surgery outcome. Conclusion . Size of seizure onset zone represent a sole stereo-EEG parameter affecting fDRE surgical treatment outcome.