Management of coagulopathy related to major obstetric bleeding: narrative review

Obstetrics Gynecology and Reproduction 2026 Open access

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Authors: L. Correa-Pérez, S. Olaya-Garay, S. Mora-Martínez
DOI: 10.17749/2313-7347/ob.gyn.rep.2025.482
Cited by: 1
References: 28

Abstract

Obstetric bleeding represents one of the main causes of maternal mortality worldwide. Along with hypertensive disorders it accounts for over half of maternal mortality cases. The implementation of strategies such as the "code red", increased institutionalized deliveries, early transfusions, and early obstetric alert system has reduced mortality. Cases of massive bleeding require admission to the Intensive Care Unit as they can progress to coagulopathy. This narrative review focuses on medications intended for the advanced management of coagulopathy in this population.

Fields of Study & Subjects

Maternal and fetal healthcare Trauma Hemostasis Coagulopathy Resuscitation Pregnancy and preeclampsia studies

Publication details

Journal / source
Obstetrics Gynecology and Reproduction
Publisher
IRBIS
Volume
19
Issue
6
Pages
914–922
Publication date
19 January 2026
Language
RU