Current view on epilepsy treatment in reproductive age women

Epilepsy is one of the most common neurological diseases, so that women account for about 50% of patients. The effect of antiepileptic drugs on women's reproductive function is an important and relevant area of medical research. It is now known that many antiepileptic drugs can have significant effects on the reproductive system, affecting both hormone levels and fertility. These effects require careful consideration while choosing therapy for women of reproductive age, especially for those who plan pregnancy or face conception problems. Despite the proven effectiveness for the currently used drugs and their variability, one third of patients achieve no permanent remission of epilepsy. Knowing the pathogenesis underlying development of this disease, in real life, drugs should be used not so much to stop seizures but rather to prevent their emergence. This article examines the mechanisms of action for antiepileptic drugs, their potential impact on reproductive function, and issues related to the management of side effects in clinical practice as well as the individual selection of the most effective and safe therapy.