Comparison of the Effects of Different Anesthetic Agents on Hemodynamics, Recovery and Postoperative Cognitive Function in Ambulatory Gynecologic Procedures

Objective: The aim of this study is to compare the effects of three different intravenous induction agents (propofol, etomidate, and thiopental) on hemodynamic parameters, recovery times, and postoperative cognitive functions in patients undergoing short-duration ambulatory vaginal gynecological procedures.Methods: This postoperative observational study included a total of 120 patients aged 25-75 years in the ASA I-II group who underwent transvaginal gynecological procedures in the Obstetrics and Gynecology Operating Room of Istanbul Training and Research Hospital between March and May 2010.Patients were divided into three groups: Group-P (Propofol 2 mg/kg), Group-E (Etomidate 0.3 mg/kg), and Group-T (Thiopental 5-7 mg/kg).All groups received 1.5 µg/ kg fentanyl for analgesia.Hemodynamic parameters, recovery times, and scores of Aldrete, Ramsay Sedation Scale (RSS) and Mini-Mental State Examination (MMSE) were recorded and analyzed.Results: Hemodynamic stability was best maintained in Group-E, while significant reductions in systolic and diastolic blood pressure were observed in Group-P at the 1 st and 5 th minutes (p