Diagnostic utility of portal vein pulsatility index in differentiating cirrhotic patients with portal hypertension from healthy controls

Background: Cirrhosis is a major global health problem, causing significant morbidity and mortality, and is characterized by progressive hepatic fibrosis that leads to portal hypertension and associated complications such as ascites, hepatorenal syndrome, and hepatic encephalopathy. The purpose of this study was to evaluate the diagnostic accuracy of portal vein pulsatility index in distinguishing cirrhotic patients with portal hypertension from healthy individuals. Methods: This cross-sectional study was conducted at the department of radiology and imaging, Bangladesh Medical University (BMU), Dhaka, Bangladesh, from January 2024 to September 2025, enrolling 60 participants (30 cirrhotic patients with portal hypertension and 30 healthy controls). Doppler ultrasonography was performed after fasting using an Esaote MyLab X8 system, and portal vein pulsatility index (PI) was calculated as (Vmax − Vmin)/Vmax. Disease severity was assessed by Child-Pugh class, and diagnostic accuracy of PI was evaluated using ROC analysis (SPSS v23.0; p