Calming contest - a battle between nitrous oxide and oral sedation - who wins in paediatric minds

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Authors: Sonal Gupta, Charu Aggarwal, Akil Prawin S.S., Rohan Shrivastava, Anuska Bhattacharjee, Aishwarya Pawar
Cited by: 0
References: 36

Abstract

Background: The aim of the study was to compare the pre and post use of oral melatonin as oral sedative drug with nitrous oxide-oxygen sedation in young uncooperative children. Methods: Twenty children aged 5 to 10 years were chosen to participate in the study and were equally divided into two groups: group 1 oral melatonin and group 2 nitrous oxide sedation. Parameters evaluated included Ramsay sedation scale, Houpt behaviour rating scale and Chota Bheem scale for anxiety, heart rate and oxygen saturation. The student t-test was used to compare the groups, and proportions were analysed using the Chi-square test. Results: The treatment carried out was successful in 80% and 73% of the children in the melatonin and nitrous oxide groups respectively with no statistically significant differences between the two groups. Conclusion: The study found that children aged 5 to 10 years can be sedated well with either of the sedative regimens. However, administering nitrous oxide oxygen sedation requires clinically higher patient compliance.

Fields of Study & Subjects

Anesthesia and Sedative Agents Dental Anxiety and Anesthesia Techniques Pediatric Pain Management Techniques

Publication details

Journal / source
International Journal of Contemporary Pediatrics
Volume
13
Issue
2
Pages
187–195
Publication date
27 January 2026