A clinico-epidemiological profile of vitiligo in female patients attending a tertiary care centre of North India and its impact on quality of life

Background: Vitiligo is a chronic acquired depigmenting disorder with significant psychosocial consequences, particularly among female patients due to cosmetic concerns and sociocultural stigma. Data focusing exclusively on females and quality of life from North India remain limited. Methods: A hospital-based cross-sectional study was conducted in the Department of Dermatology, Venereology and Leprology of a tertiary care centre in North India. Ninety female patients with clinically diagnosed vitiligo were enrolled. Demographic and clinical details were recorded. Quality of life was assessed using the dermatology life quality index (DLQI). Data were analysed using descriptive statistics and inferential tests. Results: The mean age of patients was 29.6±11.2 years. The most common age group affected was 18–30 years (42.2%). Non-segmental vitiligo was the predominant clinical type (75.6%). Facial involvement was observed in 51.1% of patients. The mean DLQI score was 10.8±4.6, indicating moderate to severe impairment of quality of life. Higher DLQI scores were significantly associated with younger age, facial involvement and unmarried status. Conclusions: Vitiligo has a significant negative impact on the quality of life of female patients, particularly younger women and those with visible lesions. A holistic management approach addressing both clinical and psychosocial aspects is essential.