Macular ganglion cell – Inner plexiform layer thickness: An early indicator of hydroxychloroquine-induced retinal toxicity
Abstract
Background: To evaluate the thickness of GC-IPL by using SD-OCT in the south Indian population receiving chronic HCQ therapy.Materials and Methods: In this cross-sectional study, 50 patients receiving HCQ therapy for a 5-year duration were compared with 50 normal subjects in the control group with no treatment history. The GC-IPL thickness was measured using SD-OCT.Results: The average GC-IPL thickness was lower in HCQ-treated group than in control subjects, with a significant p-value
Fields of Study & Subjects
Drug-Induced Ocular Toxicity
Glaucoma and retinal disorders
Retinal Diseases and Treatments
Publication details
- Journal / source
- Indian Journal of Clinical and Experimental Ophthalmology
- Volume
- 12
- Issue
- 1
- Pages
- 105–111
- Publication date
- 23 February 2026
- Language
- EN