Correlation of lipid profile with anthropometry in women with polycystic ovarian syndrome

Background: Women in their childbearing age group most commonly have PCOS, which is of Endocrine origin. PCOS can cause reproductive as well as metabolic problems. Several researches have indicated an early onset of cardiovascular risk and abnormal lipid profile in women with PCOS. Anthropometry is a simple tool in estimating the metabolic risk in PCOS women.Aims and Objectives: The objective of our study was to correlate lipid profile with anthropometric parameters in PCOS women.Materials and Methods: It was a prospective study from November 2020 to May 2022 at M.S. Ramaiah Medical College and Hospitals, Bangalore.Results: In this study, 61% had BMI > 26kg/m2. The most common anthropometric abnormality was waist circumference and the most common abnormal lipid parameter was low High Density Lipoproteins (HDL). BMI had positive correlation with serum triglycerides with P value < 0.001.BMI had positive correlation with VLDL cholesterol with P value < 0.001 and negative correlation with HDL cholesterol with P value < 0.001. Similar results were noticed with BMI and waist to hip ratio.With waist-height ratio, the positive correlation was significant with total cholesterol, serum triglycerides and negative correlation with HDL was significant. With waist circumference, it was similar. Hip circumference and lipid profile had weak correlation.Conclusion: In the present study, atherogenic dyslipidemia was common in PCOS women. BMI and waist circumference were the important anthropometric parameters correlating with dyslipidemia. PCOS women with dyslipidemia are prone for metabolic syndrome. Hence PCOS diagnosed early can be managed by life style modifications and pharmacological therapy and thereby prevent metabolic syndrome.