Systematic review and network meta-analysis of the improvement effect of psychological intervention on anxiety in patients with breast cancer

Objective: To analyze the improvement effect of anxiety state in breast cancer patients with malignant tumor after psychological intervention based on systematic review and network Meta-analysis. Methods: Randomized controlled trials (RCTS) on the effect of psychological intervention on anxiety of breast cancer patients were collected from CNKI, Wanfang database, VIP database and foreign Pubmed database, and the retrieval period was from the establishment of the database to 30 November 2025. The quality of the included studies was evaluated by Cochrane bias risk assessment tool. python software was used for network Meta-analysis. Results: A total of 11 studies involving 828 patients were included in this study, with 427 patients in the observation group and 401 patients in the control group. A total of 7 interventions were involved, including usual care, computerized cognitive behavioral therapy, Internet cognitive behavioral therapy, mindfulness-based cognitive therapy, positive psychological intervention based on PERMA model, acceptance and commitment therapy, and cognitive behavioral group therapy. Among them, the evaluation of anxiety improvement involved 12 studies, depression improvement involved 12 studies, and quality of life improvement involved 6 studies. The results of network Meta-analysis showed that mindfulness-based cognitive therapy was the best psychological intervention to improve anxiety, depression and quality of life in breast cancer patients, and the SUCRA probability was 100.00%. Conclusion: Mindfulness-based cognitive therapy has the best effect on improving anxiety, depression and quality of life in breast cancer patients, which can be prioritized for application.